Educational Articles
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Polymyxin B/miconazole/prednisolone otic (brand name Surolan), is a combination antibacterial (polymyxin B), antifungal (miconazole), and anti-inflammatory steroid (prednisolone) ear drop medication. It is used to treat ear infections in cats and dogs. It is used “off label” or “extra-label” in species other than cats and dogs and to treat conditions other than ear infections. Polymyxin B/miconazole/prednisolone otic comes in an otic suspension form.
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Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.
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Ponazuril is given by mouth and is used on and off label to treat protozoal parasites in several animal species. Side effects are uncommon but may include soft stools.
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Potassium salts are given by mouth or injection and are primarily used off label to treat low blood potassium levels. Common side effects include nausea or discomfort.
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Povidone iodine topical (brand names Vetadine®, Poviderm®, Povidine®, others) is a topical antiseptic used on the skin prior to surgery and in first aid treatments for cats and dogs. It has been used in aquatic species and reptiles to treat fungal infections and wounds. Povidone iodine topical comes in liquid solution, gel, ointment, scrub, shampoo, and spray forms.
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Pradofloxacin (brand name Veraflox®) is an antimicrobial medication used to treat bacterial infections. It is used to treat skin, urinary tract, and respiratory tract infections in cats. Pradofloxacin is approved for use in dogs in certain countries. It is used "off label" or "extra label" to treat other types of infections in cats and some types of infections in dogs.
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Pramoxine topical (Comfort; Micro-Pearls Advantage Dermal-Soothe®; Pramox-1®; Relief®, others) is a topical anesthetic (numbing agent) used to reduce pain and itching temporarily in cats, dogs, and other animals. It comes in a variety of forms that are applied directly to the skin.
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Praziquantel is given on and off label and by mouth or injection to treat various internal parasites in cats, dogs, small mammals, birds, reptiles, and large animals. Do not use in pets that are allergic to it, in puppies less than 3 weeks old, or kittens less than 6 weeks old.
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Praziquantel/pyrantel pamoate (brand name Drontal) is an oral antiparasitic drug used to treat and control hookworms, roundworms, and tapeworms in cats and kittens that are at least 8 weeks of age and weigh at least 0.9 kg (2 lb), and in dogs and puppies that are at least 12 weeks of age and weigh at least 2.7 kg (6 lb). Praziquantel/pyrantel pamoate comes in tablet form.
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Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.
